Familial polyposis coli is known as familial adenomatous polyposis. This is a hereditarily inherited ailment. Numerous adenomas become in the epithelium of the colon. They start as benevolent polyps however tend to wind up dangerous and lead to colon tumor if not treated appropriately. There are three sorts: familial adenomatous polyposis , lessened FAP likewise called inherited level adenoma disorder and autosomal latent FAP additionally called MYH related polyposis.
Familial adenomatous polyposis is the aftereffect of a hereditary change and is the most widely recognized adenomatous polyposis disorder.
FAP is quiet a rare condition and affects 1 in 10,000 people.
Genetic condition and mutation of the adenomatous polyposis coli or APC gene present in chromosome 5. The APC gene is a tumor suppressor located on band 5q21 and regulates a protein called B-catenin which is responsible for cell growth and destruction. When APC is faulty, then the cells are not controlled and manifest as polyps and can be cancerous.
Inherited from parents
Unexplained mutations which have erupted not due to inheritance
Flexible sigmoidoscopy or colonoscopy: This procedure helps in examining the lower part of the bowel via the rectum. Air is blown into the tube which is inserted into the intestine to look for polyps.
Endoscopic colonoscopy: This is done for patients with colonic symptoms to examine the digestive tract.
Genetic testing: A family history for the disease is studied and a genetic testing is done to confirm and clarify the diagnosis.
Patients with familial polyposis coli will require total proctocolectomy as this condition has a pre-malignant potential.
Laparoscopic surgery is also called minimally invasive surgery (MIS)
Surgery of the esophagus is conducted for perforation
Surgery on the small intestine is one of the most frequently done
Collection of pus in the liver is a common occurrence
Colorectal surgery is required for disorders of the colon, rectum
Pancreaticoduodenectomy (Whipple Procedure)
Individuals suffering from morbid obesity undergo gastric bypass
Gallbladder stones are an extremely common disorder
Metabolic and bariatric surgery is the treatment of morbid
GI Bleeding is an emergency. Patients present with massive
The portal venous system comprises of the portal vein